Professor Alex Rothman
MA, BM BCh, MRes, PhD, MRCP, EEGC
School of Medicine and Population Health
Professor of Cardiology
Honorary Consultant Cardiologist
+44 114 215 9521
Full contact details
School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I trained in medicine at Cambridge and Oxford, and joined the University of Sheffield in 2008 as an Academic Clinical Fellow.
Following an MRC Clinical Research Training Fellowship, an NIHR Clinical Lectureship and a Wellcome Trust Clinical Research Development Fellowship I am now an Honorary Consultant Cardiologist and Academic Training Lead at Sheffield Teaching Hospitals NHS Trust, and Professor of Cardiology at the University of Sheffield.
- Research interests
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Our translational studies have developed new drugs and devices that now have regulatory approvals and established reimbursement. Our current work focuses on the pathology and physiology of pulmonary hypertension and heart failure, and the development of novel therapeutic strategies, clinical trial methodologies and remote clinical evaluation. Fellows and students working with the group have been awarded national and international awards, and gained external funding for their research.
Current projects
- MRC Experimental Medicine: Pulmonary Hypertension: intensification and personalisation of combination Rx (PHoenix), £1.7m MRC, £0.5m Abbott, (PI), MR/W026279/1
- Sotatercept extension of PHoenix, £1m (PI)
- MRC DPFS: Emapunil for pulmonary arterial hypertension, £1.9m (Co-I), APP57948
- EPSRC Project: CVD-NET - Networks of Cardiovascular Digital Twins, £10m (Co-I and clinical study lead), EP/Z531297/1
- EPSRC Project: GLUTRONICS - Glucose-fuelled ultra-low power implantable bioelectronics, £2.2m (Co-I), EP/Z536027/1
- Innovate UK Innovate UK Biomedical Catalyst: Addition of continuous cardiac output measurement to improve care of chronic cardiac patients at home, £500k (Co-I)
- Innovate UK Biomedical Catalyst: Comprehensive remote monitoring system for Congestive Heart Failure, £499k (Co-I), TS/Y02477X/1
- BHF Clinical Research Training Fellowship: Assessment of fluid status in animal models of heart failure and pulmonary Hypertension, £313k, FS/CRTF/23/24465
- NIHR Efficacy and Mechanism Evaluation: Positioning Imatinib for Pulmonary Arterial Hypertension, £1.2m (Co-I), NIHR128465
- BHF Innovation Award, £300k (PI), HI/B3/24/370100
- Publications
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- Teaching interests
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I enjoy lecturing clinical cardiology to both undergraduates and post-graduates and I teach clinical skills to medical students and doctors.