TY - JOUR T1 - An enzyme with high catalytic proficiency utilizes distal site substrate binding energy to stabilize the closed state but at the expense of substrate inhibition JO - ACS Catalysis PY - 2022/02/14 AU - Waltho J AU - Robertson A AU - Cruz-Navarrete FA AU - Wood H AU - Vekaria N AU - Hounslow A AU - Bisson C AU - Cliff M AU - Baxter N ED - PB - American Chemical Society Y2 - 2025/08/07 ER -